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半胱胺对成年鹅血浆中生长抑素和某些代谢激素的影响
EFFECTS OF CYSTEAMINE ON THE PLASMA LEVELS OF SS AND SOME METABOLIC HORMONES IN ADULT GEESE
【摘要】 目的 :研究半胱胺 (CS)对成年鹅生长抑素 (SS)和某些代谢激素的影响。方法 :14只装有翅静脉瘘管的成年杂交鹅 (川白×太湖 ) ,经瘘管采取对照期和处理 (一次性添喂 10 0mg/kgbw的半胱胺 )后第 1、3、5、7d的血样 ,用RIA双抗法测定其中激素的含量。结果 :实验期第 1、3、5和 7d的生长抑素的含量均显著低于对照期 (1.89± 0 .10μg/L)。促甲状腺激素较对照期 (2 .4 5± 0 .31mIU/L)在第 1d显著下降 2 1.6 3% (P <0 .0 5 ) ,第 3、5d均降低18.37% (P >0 .0 5 ) ,第 7d基本回复正常 (P >0 .0 5 )。实验期 1、3、5和 7d的T4较对照期 (5 .4 1± 0 .98μg/L)显著升高 (P <0 .0 1) ;实验期第 3d的T3 水平较对照期 (1.0 5± 0 .0 6 μg /L)高 36 .19% (P <0 .0 1) ;同样 ,胰岛素在实验期的第 5d显著高于对照期 (P <0 .0 5 )。结论 :CS能够降低成年鹅血液中SS含量 ,使T4、T3 和胰岛素水平升高 ,提高了机体的代谢水平 ,同化作用加强 ,从而有利于生长。
【Abstract】 Aim: To know the effect of cysteamine (CS) on the plasma levels of somatostatin (SS) and some metabolic hormones in adult geese. Methods: Fourteen adult crossbred geese (Chuan white ×Tai lake) fitted with chronic wing vein cannulas were used in this study to evaluate the effect of CS on SS,TSH,T 3 and T 4 levels. The experiment was consisted of control and treated phase. The diet was added CS at dosage of 100 mg/kg bw on the first day of the treated phase. The blood samples were collected from the cannulas and analyzed by radioimmunoasssay. Results: The plasma SS concentration was (1.87±0.10)μg /L in control phase. Whereas SS concentrations on day 1,3,5,7 of treated phase were decreased markedly (P<0.05 or P<0.01). Thereafter it was rose on the seventh day,however it was still lower than that of control. The thyroid stimulating hormone (TSH) content (2.45±0.31 mIU/L) was significantly decreased by 21.63% (P<0.01) on day 1,and 18.37% (P>0.05) on day 3 and day 5. Comparing with control phase (5.41±0.98 μg/L),T 4 contents were elevated by 60.26% (P<0.01),43.25% (P<0.01)?37.15% (P<0.01) and 16.82% (P<0.01) respectively on day 1,3,5,7. T3 level was (1.05±0.06)μg/L in control phase,whereas the levels was significantly increased by 36.19% (P<0.01) on day 3. Also,the insulin concentration was higher than that of control (4.43±0.41 mU/L) by 18.28% (P<0.05) on the day 5. Conclusion: These results indicate that CS can decrease the plasma SS and TSH levels,whereas increase the levels of T 4,T 3 and insulin,therefore change metabolism,improve the nutrition transform and accelerate the growth in geese.
- 【文献出处】 中国应用生理学杂志 ,Chinese Journal of Applied Physiology , 编辑部邮箱 ,2004年01期
- 【分类号】S852.2
- 【被引频次】9
- 【下载频次】104