【摘要】 目的:评价淋巴显像技术在口腔鳞癌哨位淋巴结活检中的价值。方法:应用颈淋巴显像技术结合蓝染法及SPECT/CT同机融合技术,对21例临床NO(cNO)口腔鳞癌患者的哨位淋巴结(sentinel lymph node,SLN)进行研究。结果:全组患者SLN检出率为100％,21例中有7例SLN活检阳性,颈清术后标本同样证实有颈淋巴结转移,无假阴性结果,SLN活检对全组病例颈淋巴结转移状况预测的准确性为100％。结论:颈淋巴显像技术结合蓝染法及SPECT/CT同机融合技术能有效地对口腔鳞癌SLN进行定位,从而准确预测颈淋巴结转移状况。更多还原

【Abstract】 PURPOSE: To assess the clinical value of lymphoscintigraphy in detecting sentinel lymph node (SLN) in oral squamous cell carcinoma. METHODS:Sentinel lymph node of twenty-one patients with oral squamous cell carcinoma without clinical lymph metastasis (cN0) were investigated using lymphoscintigraphy combined with methylene blue or a hybrid SPECT/CT system. RESULTS: SLN was successfully identified in all of the 21 patients, 7 (33.3%) cases were found lymph node metastasis positive pathologically . The samples of elective neck dissection also contained tumor cells in these 7 patients . There were no false negatives and the accuracy rate of SLN was 100%. CONCLUSIONS: The detection of SLN using lymphoscintigraphy combined with methylene blue or a hybrid SPECT/CT system could accurately identify the SLN and predict cervical lymph node metastasis in oral squamous cell carcinoma.更多还原