【摘要】 目的　寻求倍频Nd∶YAG激光击穿犬眼视网膜全层 (含Bruch膜 )的最佳激光参数 ,为临床提高激光诱导脉络膜视网膜静脉吻合支的成功率提供实验依据。方法　以不同激光参数击射犬眼视网膜的不同部位 ,用HE染色的组织切片和KS 4 0 0型图像分析系统验证击射效果。结果　激光功率、光斑直径与击射部位对击穿犬眼视网膜层次均有影响 (P =0 0 0 0 1 ) ,击穿犬眼视网膜全层 (含Bruch膜 )的激光参数组合为 :1 2～ 1 8W、5 0 μm、0 1s ;1 8W、1 0 0 μm、0 1s。结论　倍频Nd∶YAG激光击穿犬眼视网膜全层 (含Bruch膜 )的最佳参数为 1 2～ 1 5W、5 0 μm、0 1s。更多还原

【Abstract】 Objective To explore the optimal parameter of 532 nm wavelengthed laser in penetrating the whole retina (including Bruch′s membrane) of dog′s eyes and to provide experimental data for improving the successful rate laser-induced chorioretinal venous anastomosis Methods Different retinal sites were photocoagulated with different parameters , and the effect was assessed by histological examination and the KS 400 image pattern analytic system Results The penetrated retinal level was influenced by the power, the size of spot and the photocoagulated sites ( P =0 0001) The combined parameters of 532 nm wavelengthed laser application for penetrating full-thickness retinal including Buch′s membrane are 1 2～1 8 W, 50 μm, 0 1 s, 1 8 W, 100 μm, 0 1 s Conclusions The optimal parameter of penetrating full-thickness retina is as follows : power ranging from 1 2～1 5 W, the size of spot at 50 μm and duration at 0 1 s更多还原