【摘要】 目的　采用CT扫描研究阻塞性睡眠呼吸暂停综合征 (OSAS)、单纯鼾症患者及正常人之间上气道结构与功能的差异 ,评价CT对上气道疾病的诊断价值。方法　对 16 6例OSAS患者、6 8例单纯鼾症和 34例正常人的上气道进行CT扫描 ,测量并计算其上气道截面积。结果　正常人上气道最小截面积为 (1 79± 0 5 8)cm2 ,均位于口咽上部 ;单纯鼾症组为 (1 0 6± 0 36 )cm2 ,最狭窄部位也多位于口咽上部 ;OSAS组为 (0 74± 0 4 9)cm2 。多数OSAS患者上气道口径在平静呼吸与深吸气后屏气之间变化较为明显 ,96例 (96 / 12 2 )患者在深吸气后屏气时口咽部截面积明显减少 ,其中 4 7例在深吸气后的一个或数个层面上出现完全阻塞图像 ,平静呼吸与深吸气后的变化范围为 (1 0 8±0 14 )cm2 。 32例单纯鼾症患者中 17例在深吸气后口咽部截面积减少 ,但变化幅度较小 ,为 (0 2 9±0 37)cm2 ,未发现完全阻塞者。对照组有 12例 (12 / 16 )在深吸气后口咽部截面积减少 ,均较单纯鼾症组轻 ,其减少值仅为 (0 17± 0 0 9)cm2 。结论　上气道CT检查有助于明确OSAS患者上气道阻塞的原因及程度 ,有较高的诊断价值。更多还原

【Abstract】 Objective To study the characteristic alterations of the upper airway structure and function in patients with obstructive sleep apnea syndrome(OSAS),healthy snorers and healthy subjects with CT scan to evaluate CT scan’s value in diagnosis and treatment of OSAS.Methods 166 patients with OSAS,68 healthy snorers and 34 healthy subjects were enrolled in the study.The upper airway area was measured and evaluated using CT canner.Results The area of upper airway of patients with OSAS and healthy snorers is narrower than that of heahthy subjects.The patients with OSAS had more stricture sites in upper airway than the other subjects.Conclusion Upper airway CT scan could play an important role in diagnosis and treatment in OSAS especially in the way of surgical choice.更多还原