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每天1次吸入普米克气雾剂治疗儿童轻度持续哮喘疗效评价
The effectiveness of once-daily vs twice-daily dosing of inhaled budesonide in mild persistent asthma in children
【摘要】 目的 评价每天吸入 1次普米克气雾剂 (2 0 0 μg/d)治疗儿童轻度持续哮喘的疗效。方法 随机选择轻度哮喘患儿各 35例作为试验组和对照组 ,分别应用普米克气雾剂 2 0 0 μg/d ,每日1次 ;4 0 0 μg/d ,每日 2次 ,均治疗 6个月 ,评价治疗前、后的临床症状和峰流速 (PEF预计值 % )的变化。结果 试验组总有效率 80 0 % ,对照组总有效率 85 7% ,两组疗效比较无显著性差异 (P >0 0 5 ) ;试验组和对照组治疗前、后PEF均有显著性差异 (P <0 0 1) ,治疗后两组PEF无显著性差异(P >0 0 5 )。结论 对轻度持续哮喘患儿每天 1次吸入普米克气雾剂与每天 2次吸入同等剂量疗效相当。
【Abstract】 Objective To evaluate the effects of one-daily inhaled budesonide (BUD) on mild persistent asthma in children.Methods 70 mild persistent bronchial asthmatic children were enrolled and randomly inhaled budesonide of 200 μg/d once-daily or twice-daily respectively for 6 months.The symptoms scores and peak expiratory flows in the morning and evening before and after treatment were recorded and compared.Results No significant differences of symptoms scores and peak expiratory flows were found between the patients receiving once-daily and twice-daily budesonide inhalation.Conclusion For mild persistent asthma children once-daily inhalation of budesonide is equivalent to twice-daily inhalation to get good control of asthma.
- 【文献出处】 中国呼吸与危重监护杂志 ,Chinese Journal of Respiratory and Critical Care Medicine , 编辑部邮箱 ,2004年01期
- 【分类号】R725.6
- 【被引频次】7
- 【下载频次】37