【摘要】 目的　了解城市学龄儿童血脂水平的现状及其影响因素 ,为消除儿童心血管疾病危险因素提供科学依据。方法　采用多阶段抽样 ,抽取石家庄市区 913名 7～ 13岁儿童 (男 4 2 6人 ,女 4 87人 ) ,对其血压、身高和体重进行测量 ,并采空腹静脉血测定总胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白胆固醇 (HDL -C)、血糖和血钙。通过问卷获得儿童饮食习惯、生活方式和家族史等影响因素。结果　TC和HDL -C随年龄增长呈下降趋势 ,TG随年龄增长变化趋势不明显。TC、TG和HDL -C的异常检出率分别为 8 9% ,5 6 %和 6 0 %。对TC作用显著的影响因素为TG、HDL -C和年龄 ;TG的影响因素为TC、HDL -C、体重指数 (BMI)、血钙、父母高血脂史和性别 ;影响HDL -C的因素为TC、TG、血钙、BMI、甜食次数和吃水果次数。结论　控制儿童血脂异常及消除以上不良因素 ,将有助于消除儿童心血管疾病危险因素 ,从而有效地防止儿童期心血管疾病的发生 ,并降低儿童期危险因素对成人心血管疾病发生的危险性更多还原

【Abstract】 Objective To explore the disrtributing characteristics and influencing factors of blood lipids in urban schoolchildren,and to offer the scientific basis for eliminating cardiovascular disease risk factors in schoolchildren.Methods 913 schoolchildren aged 7-13 were chosen randomly among Shijiazhuang city by multi-stage sampling.Blood pressure,height and weight were measured.Fasting blood serum was collected to determine total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),fasting serum glucose and blood calcium.The children’s dietary status,behavior,personality and family history were obtained by offering and collecting questionnaires for each child.Results TC and HDL-C of schoolchildren showed a tendency to drop with age increasing,but it was not obvious for TG to change with age increasing.Prevalences of abnormal TC,TG and HDL-C were 8.9%,5.6% and 6.0% respectively.Multiple stepwise regression analysis showed that TG,HDL-C and age were influencing factors for TC;TC,HDL-C,BMI,blood calcium,family history of parents’ hyperlipidemia and sex for TG;and TC,TG,blood calcium,BMI,frequency of eating sweet food and fruits for HDL-C.Conclusion Controlling abnormal blood lipids in children and eliminating adverse influencing factors would be helpful to eliminate cardiovascular disease risk factors in children,and protect children from cardiovascular diseases and reduce risk factors resulting in cardiovascular diseases in aduldtood.更多还原