【摘要】 目的　分析比较铜绿假单胞菌 (PA)医院感染与外环境中PA的相关性 ,以了解医院感染病原菌来源。方法　比较PA医院感染株、社区感染株、环境株的耐药谱以及随机引物扩增多态性基因分型 (RAPD)型别之间的差异 ,判断三者之间的相关性。结果　收集PA医院感染株 18株 ,社区感染株 17株 ;1190份环境样中共分离到PA2 1株 ,环境分离率为 1 76 %。耐药谱与RAPD分型表明医院感染株与社区感染株、环境株之间无明显相关性。结论　铜绿假单胞菌医院感染可能以内源性途径为主更多还原

【Abstract】 Objective To detect the correlation of the pseudomonas aeruginosa(PA) from inpatients with NI,inpatients without NI and from the hospital environment.Methods To compare the differences of drug-fast pathogens and RAPD pathogens between the PA from inpatients with NI and the PA from inpatietns without NI and the hospital environment so as to determine correlation between the three PA pathogens.Results To collecete 18 strains PA from inpatients with NI,17 strains PA from inpatients without NI,from the hospital environment and to isolate 21 strains of PA.Environment isolated rate was 2.52%.Study on the drug-fast pathogens and RAPD pathogens indicated that there was no obvious correlation between the PA from inpatients with NI and from inpatients without NI and from hospital environment.Conclusion The most PA NI were derived form the patients themselves,more importane should be attached to improve the patients resistibility so as to prevent NI.更多还原