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超声引导药物注射结合高强度聚焦超声治疗门静脉癌栓的初步临床观察

Preliminary Clinical Observation on Interventional Oily C hemoembolization Guided by US Combined with HIFU for Treatment of Embolization in Portal Vein

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【作者】 朱辉陈文直黎克全苏海兵金成兵张欲晓曹玲

【Author】 Zhu Hui,Chen Wenzhi,Li Kequan,et al Clinical Center for Tumor Therapy,2 nd Affiliated Hospital of Chongqing Med ical University,Chongqing 400010 China

【机构】 重庆医科大学附属第二医院肿瘤中心重庆医科大学附属第二医院超声科重庆医科大学附属第二医院超声科 400010重庆市400010重庆市

【摘要】 目的 :探讨超声引导下门脉癌栓穿刺注射结合高频聚焦超声 (HIFU)技术治疗门脉癌栓的安全性和有效性。方法 :8例合并门脉主支癌栓的原发性肝癌患者在超声引导下穿刺在癌栓内注入碘油化疗药物混悬液并接受 HIFU治疗。结果 :1例患者出现肠系膜上静脉异位栓塞 ,无其它相关并发症出现 ,X-线摄片示门脉癌栓内碘油致密沉积 ,MRI或 CT检查示门脉癌栓血供消失 ,随访 4例患者门脉癌栓缩小或消失。结论 :超声引导下门脉癌栓内药物注射结合 HIFU技术是一种安全和有效治疗门脉癌栓的方法

【Abstract】 Objective:To explore the safety and efficacy of using inject ion of iodized oil into portal venous emboli guided by US combined with HIFU to treat embo lization in portal vein.Methods:Eight patients with primary liver cancer complicated w ith embolization in portal vein underwent iodized oil suspension injection into portal vein guided by US and afterwards HIFU treatment.Results:One patient appeared ectopic embolism in mesentery vei n,and other patients had no complications.X-ray examination showed pykno-depo sition of iodized oil in the emboli.MRI or CT examination demonstrated blood-su pply disappeared in the emboli.In the fellow-up,4 patients had shreaked or disa ppearance of emboli.Conclusions:Iniecting drug into the emboli in portal vein guid ed by US combined with HIFU for treatment of embolization in portal vein is a sa fe and effective therapeutic method.

【基金】 国家“九五”重点科技攻关项目 ( No. 96 - 90 5- 0 2 - 0 1);国家自然科学基金委重点项目 ( No. 396 30 34 0)
  • 【文献出处】 中国超声医学杂志 ,Chinese Journal of Ultrasound In Medicine , 编辑部邮箱 ,2004年01期
  • 【分类号】R735.7
  • 【被引频次】26
  • 【下载频次】105
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