【摘要】 目的 :观察危重症患儿静脉注射谷氨酰胺 (Glutamine,Gln)后预防胃肠功能障碍的作用。方法 :将 32例危重症患儿分为治疗组及对照组 ,在常规治疗的基础上 ,治疗组加用 Gln0 .2 g/ kg/ d,连用 5 d,连续监测患儿胃肠功能、危重症评分、炎症介质等指标。结果 :疗程完成后 ,治疗组 0 / 16例、对照组 5 / 16例发生胃肠功能障碍 ,两组炎症介质水平无显著性差异。结论 :对危重症患儿早期应用较小剂量 Gln有助于保护胃肠功能更多还原

【Abstract】 Objective:To observe the action of intravenous glutamine on prevention of gastrointestinal dysfunction in critically ill children.Methods:32 critically ill children were randomized into intervention group and control group,both groups received conventional treatment based on primary diseases,patients in intervention group additionally received intravenous glutamine 0.2g/kg/d for connective 5 days,and patients’ gastrointestinal dysfunction,critical illness score,and inflammatory mediators’ levels were constantly monitored.Results:After therapy,0/16 in intervention group,5/16 cases in control group had gastrointestinal dysfunction,no difference was found between two groups.Conclusion:Low dose glutamine used early can prevent gastrointestinal dysfunction in critically ill children.更多还原