【摘要】 目的以孕妇和新生儿作为重点研究目标,了解郑州市碘营养现况。方法用国家规定的检测方法测定盐碘和孕妇尿碘;采用免疫放射分析(IRMA)国产试剂测定新生儿脐带血TSH。结果(1)碘盐合格率控制在国家规定的标准内。(2)孕妇早、中、晚孕期尿碘中位数分别为231.40、212.44、192.25μg/L,以晚期偏低,但在3 111份尿样中仍有516份尿碘中位数< 100 μg/L,说明部分孕妇和胎儿仍处于严重缺碘状态中;选择连续采2期以上尿样的728名孕妇进行尿碘连续观察,孕妇晚期尿碘水平与新生儿TSH值高度相关(r= 0.65,P< 0.01)。结论持续消除碘缺乏病应加大宣传力度,指导孕妇合理补充碘营养,确保儿童的健康生长。更多还原

【Abstract】 Objective To know the present iodine nutritive condition. Methods Salt iodine and urine iodine were tested by national standard methods. IRMA was used to examine newborn’s whole blood (umbilical cord blood). Results (1) The qualified rate of iodine salt was within the national standard. (2) Three periods (phase, midterm, later period) urine sample of pregnant women’s were collected, and the median of urine iodine was 231.40,212.44,192.25 μg/L, respectively, the late period’s median was on a low side obviously; among the 3 111 urine samples, there were 516 samples with median of urine iodine < 100 μg/L, which means some pregnant women and fetus were in the state of serious iodine deficiency; 728 women were sampled of their urine iodine in pregnant women,and the iodine level was highly related with TSH in newborns(r = 0.65, P < 0.01). Conclusions The education of eliminating iodine deficiency disorders should be strongly increased, and it should focus on instruct pregnant women complementing iodine nutrition in late period of pregnancy, to insure the newborn’s health.更多还原