【摘要】 目的了解燃煤型砷中毒患者红细胞(RBC)免疫功能与脂质过氧化关系。方法将燃煤型砷中毒患者分为轻、中、重3组,选择距病区12km外的非燃用砷煤居民作对照组,分别检测各组RBC免疫功能和血浆MDA、SOD、GSH鄄Px,并分别与对照组比较。结果燃煤型砷中毒患者RBC免疫功能损伤RBC鄄ICR高于对照组,RBC鄄C3bRR低于对照组,患者MDA高于对照组,而SOD、GSH鄄Px则低于对照组。结论氧化自由基堆积造成脂质过氧化损伤,这可能是患者RBC免疫功能受损的重要原因。更多还原

【Abstract】 Objective To study the relationship between RBC immunity and lipid peroxidation of arsenism patient.Methods The activity of superoxide dismutase(SOD),glutsthione peroxidase(GSH-Px),malondial dehyde(MDA),RBC-ICR and RBC-C 3 bRR in the blood of patients were measured and analysed.Results Compared with those of the control,the SOD,GSH-Px and RBC-C 3 b RR levels were lower(P<0.05),while the MDA and RBC-ICR levels were higher(P<0.05).Conclusions It is suggested that lipid peroxidation might be one of the reasons causing RBC immunity damage.更多还原