【摘要】 目的　探讨淋巴结炎性假瘤的临床病理学和免疫表型特点。方法　对 1例发生在颈淋巴结的炎性假瘤进行光镜观察和免疫学标记。结果　镜下示淋巴结结构破坏 ,大量增生的梭形细胞将淋巴结分隔成结节状 ,部分区域梭形细胞呈席纹样排列。免疫表型 :梭形细胞Vim、CD6 8和Mac387(+) ,actin弱 (+) ;S 10 0、CD2 1、ALK 1和desmin(- )。淋巴细胞呈多克隆性 ,以T淋巴细胞为主。结论　淋巴结炎性假瘤是发生在淋巴结的一种特殊的炎性反应 ,手术切除可完全治愈。但需要与淋巴结内的一系列梭形细胞肿瘤相鉴别。更多还原

【Abstract】 Objectine To describe the clinical, histological and immunohistochemical features of inflammatory pseudotumor (IPT) in lymph nodes . Methods One case of IPT in cervical lymph node was studied by light microscopy and immunohistochemistry. Results Microscopically, the architecture of lymph node was totally effaced by hyperplastic spindle cells, and nodular appearance was formed with sclerosing band. Partial areas had storiform pattern. Most spindle cells were positive for Vim, CD68 and Mac387, focal positive for actin and negative for CD21, S-100, ALK-1 and desmin. Lymphocytes were polyclonal, and most of them were T cell phenotype. Conclusion IPT in lymph node is a kind of special inflammatory process reacted to unknown pathogen. Surgical resection can eradicate all clinical complaints. Meanwhile IPT needs to be differentiated from a series of spindle cell tumors in lymph nodes.更多还原