【Abstract】 The GeCl 3, Ge(OH) 3, GeO 3 and GeO 1/2 moieties have been introduced to sulfonyldianiline, carbamazepine and norfloxacin, respectively, to give four medicines containing germanium. The structures of the medicines prepared were characterized by IR, 1H NMR and elemental analysis. The biological tests showed that the new compounds have anticancerous activity, among them the compound prepared from sulfonyldianiline(2000-1) has inhibitory rate of 88 6% at dosage of 1×10 -4 mol/L.更多还原