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维库溴铵治疗重度硫丹中毒7例
Treatment of Severe Endosulfan Poisoning by Vecuronium Bromide
【摘要】 目的 :探索用维库溴铵抢救重度硫丹中毒后剧烈抽搐的治疗效果。方法 :重度硫丹中毒患者 12例 ,按治疗方法分为两组 ,治疗组 5例 ,用维库溴铵注射液 0 .0 3~ 0 .0 6mg·kg 1 ·h 1 静脉微泵维持 5~ 2 8h ;对照组 7例 ,1h内用地西泮注射液 60~ 10 0mg分次静脉注射 ,随后用 10 0mg静脉滴注维持 ,同时用甘露醇 ,氨茶碱 ,抗生素等综合治疗。结果 :治疗组在死亡率 ,后遗症 ,住院周期 ,控制抽搐时间上明显优于对照组。结论 :维库溴铵治疗重度硫丹中毒是一种有效的新方法
【Abstract】 Objective:To explore the effective therapy for severe convulsions after endosulfan poisoning by vecuronium bromide. Methods:Twelve suitable patients were randomized into two groups. Five cases in the treatment group received injection of vecuronium bromide 0.03~0.06 mg·kg -1·h -1 by micro-pump maintaining for 5~28 h. Seven in the control group were injected with diazepam 60~100 mg within one hour first, and 100 mg for maintaining therapy. Results:The mortality, sequela, the in-hospital time and time for convulsion control in the treatment group were significantly superior than that in the control group. Conclusion:Vecuronium bromide is an effective method to treat severe endosulfan poisoning.
- 【文献出处】 医药导报 ,Herald of Medicine , 编辑部邮箱 ,2004年07期
- 【分类号】R595.4
- 【被引频次】2
- 【下载频次】56