【摘要】 目的在作“成人接种BCC预防结核、肿瘤等病群组对照监测研究”中,恰逢流行性感冒(流感)暴发,随即对研究对象进行流感发病情况的调查,探讨成人接种BCG对流感的预防作用。方法选一个乡的20～55岁健康村民,随机分为接种BCG的研究组和未接种的对照组。对接种组于1997年5月首次接种,11月第2次接种,1998年5月第3次接种,以后进入观察监测期,对发生的相关疾病由防疫网络医生及时进行调查、登记,每月报告,年底小结。1999年8月发生流感暴发,立即对它作专题调查,从中核对出接种组和未接种组中流感的发生情况并进行统计分析。结果①本次流感暴发,该镇在家的研究对象计7079人,发生流感者425人,其中未接种BCG的是3498人,发生流感337人,接种BCG的3581人,发生流感88人,两群组间流感的发病率相比较有非常显著差异;②接种BEG 1次的2261人,发生流感50人,接种2次的1016人,发生流感26人,接种3次的304人,发生流感12人。经统计学处理,BCG不同接种次数群组间流感的发病率无显著差异(X~2=3.430,P=0.180)。结论①成人接种BEG后约2.5年对流感有很好的预防作用(保护率74.49％);②成人接种BCG预防流感在约2.5年中不必要加强免疫,即这期间复种不能再提高机体对流感的预防作用。更多还原

【Abstract】 Objective To Observe the preventive effect on Influenza in the adut with BCG vaccination, aiming at tuberculosis and tumors during Influenza outbreak. Methods During the Influenza out break in August 1998, the healthy villager between the age of 20 to 55 in a coun- tryside town were randomly divided into two groups : BCG inoculation and control. Among the BCG group, the subject had first inoculation in May 1997 , the second in November 1997, and the third in May, 1998. Results There are 88 influenza eases of 3581 in the BCG inoculated group and 337 cases of 3498 in non - inoculated group, the incidence difference between two groups is highly significant and vaccination times have no statistical significant difference (X~2 = 3.430, P = 0.180) . Conclusion BCG plays an active role in preventing influenza and there is no significant difference statistieally in terms of inocutation frequency.更多还原