【摘要】 <正> 扣子七为五加科人参届植物大叶三七Panaxjaponicus C.A.Mey.var.major(Burkill)C.Y.Wu et K.M.Feng的干燥根茎,分布于云南,重庆,湖北等地。在渝东鄂西,扣子七用于养阴,清肺,散淤,止血,定痛,其化学成分的研究尚未见报道。 本实验以HPLC分离扣子七中人参皂苷,用离更多还原

【Abstract】 Aim To analyze the ginsenosides in Kou zi qi （rhizomes of Panax japonicus C.A. Mey. var.major （Burkill） C. Y.Wu et K. M. Feng）, and to supply evidences for chemotaxanology of Panax species andclinical uses of Kou zi qi. Methods The ginsenosides were isolated by HPLC, then the positive- and negative-ion APl-MS/MS of constituents collected from HPLC were measured. Results Eight ginsenosides wereidentified as ginsenoside Re, ginsenoside Ro, chikuseksusaponins Ⅳ, Ⅳa, notoginsenoside R₂, ginsenosidesRb₁, Rc and Rd, respectively, based on comparison of retention time with those of standards by HPLC, andanalysis on their API-MS/MS data. Ginsenoside Ro and chikuseksusaponin Ⅳa are the major components of Kouzi qi. Conclusion This plant had a close relationship to P. stipuleanatus, P. zinginensis and P.japonicus varmajor; a relatively remote relationship to P. ginseng and P. quinquefolius, in a view of chemotaxanology.Ginsenoside Ro and chikuseksusaponin Ⅳa might be the anti-inflammatory constituents of Kou zi qi.更多还原