【摘要】 探讨了天麻素及其类似小分子酚性糖甙化合物的化学合成工艺,改进了两步关键的反应:溴代乙酰糖基化合物中间体的合成;溴代乙酰糖基化合物中间体与酚性化合物缩合,生成乙酰基保护的酚性糖甙化合物.改进的工艺减轻了环境污染,提高了产率,更适合工业生产.更多还原

【Abstract】 The improved synthetic procedure of Gastroding and phenolic glycosides is reported. There are two key steps in the procedure. The first is the acetylation and halogenation of glucose or other sugars, the second is the glycosylation of phenolic compounds or the formation of phenolic glycosides. The improved procedure avoids the pollution to the environment and enhances the yield, so it benefits to the production of industry.更多还原