节点文献
2-芳基-2-吗啉醇的合成
Synthesis of 2-Aryl-2-morpholinol
【摘要】 醇胺分别与 2 溴 4′ 甲氧基苯乙酮、2 溴 3′ 氯苯丙酮、2 溴 4′ 苄氧基苯基丙酮、2 溴 4′ 苄氧基苯戊酮、6 甲氧基 2 溴乙酰基萘和 6 甲氧基 2 ( 2 溴丙酰基 )萘反应 ,合成相应的 2 芳基 2 吗啉醇 (产率 80 .7%~ 97.5 % )及其盐酸盐 .其结构经1HNMR ,IR ,MS确证
【Abstract】 Aryl-2-morpholinols were synthesized via the reactions of aminoalcohol with 2-bromo-4′-methoxyacetophenone, 2-bromo-4′-chloropropiophenone, 2-bromo-4′-benzyloxypropiophenone, 2-bromo-4′-benzyl~oxy~pento~phen~one, 6-methoxy-2-bromoacetylnaphthalene and 6-methoxy-2-(2-bromopropionyl)naphthalene by divergent synthetic method with yields of 80.7%~97.5%, respectively. The structures of 2-aryl-2-morpholinols were confirmed by 1H NMR, IR and MS spectra.
【关键词】 2-芳基-2-吗啉醇;
2-芳基-2-吗啉醇盐酸盐;
氨化;
合成;
【Key words】 aryl-2-morpholinol; 2-aryl-2-morpholinol hydrochloride; amination; synthesis;
【Key words】 aryl-2-morpholinol; 2-aryl-2-morpholinol hydrochloride; amination; synthesis;
- 【文献出处】 有机化学 ,Chinese Journal of Organic Chemistry , 编辑部邮箱 ,2004年08期
- 【分类号】TQ463
- 【被引频次】13
- 【下载频次】195