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3-甲基犬尿喹啉酸衍生物的合成
Synthesis of 3-Methylkynurenic Acid Derivatives
【摘要】 报道了六个具有潜在生物活性 3 甲基犬尿喹啉酸衍生物的合成 .它们以取代苯胺和 3 甲基 2 酮丁二酸二乙酯为起始原料 ,经加成脱水 ,环化而得到 .其中三个新的含氟化合物的结构分别经IR ,1 HNMR ,MS ,元素分析等表征
【Abstract】 Six derivatives of 3 methylquinoline acids having latency biological activity were synthesized by addition of substituted anilines to ethyl ethoxalylpropionate and followed by high temperature cyclization. Among them, three new compounds containing fluorine were identified through elemental analyses, 1H NMR, IR and MS spectra.
【关键词】 取代苯胺;
3-甲基犬尿喹啉酸;
含氟化合物;
【Key words】 substituted aniline; 3 methylquinoline acid; compounds containing fluorine;
【Key words】 substituted aniline; 3 methylquinoline acid; compounds containing fluorine;
- 【文献出处】 有机化学 ,Chinese Journal of Organic Chemistry , 编辑部邮箱 ,2004年04期
- 【分类号】O626
- 【被引频次】3
- 【下载频次】145