【摘要】 目的　研究急性白血病患者治疗前后催乳素 (PRL)和IL 11的浓度变化及其临床应用。方法　用放射免疫分析法和ELISA法分别测 3 0例急性白血病患者化疗前后PRL和IL 11浓度。结果　急性白血病治疗前PRL明显高于正常对照组 (P <0 0 1) ,而完全缓解后PRL与正常对照组比较无显著性差异 (P >0 0 5 ) ;治疗前和完全缓解后IL 11与正常对照组比较有显著性差异 (P <0 0 1) ,IL 11浓度与血小板数之间呈正相关。结论　催乳素和IL 11联合检测对于监测病情 ,疗效判断和指导治疗有参考价值。更多还原

【Abstract】 Objective To study concentration and clinical significance o f serum PRL and IL-11 in acute leukemia before and after the chemotherapy. Method Serum PRL concentrations in 30 acute leukemia before and a fter the chemotherapy were detected by RIA and serum IL-11 concentrations were detected by ELISA. Results PRL levels before treatment signif icantly higher were than the normal group (P<0.01); there are no more sign ificant level of PRL after CR than the normal group (P>0.05); IL-11 level before treatment and after CR there were more remarkably significant than the n ormal group (P<0.01); IL-11 concentrations were positively correlated wit h PLT. Conclusion PRL and IL-11 can be detected together, wh ich has important value in inspecting the state of an illness, estimate curative effect and direct therapy.更多还原