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89Sr治疗骨质疏松性骨折的临床研究
Clinical study of strontium-89 for treating osteoporotic fracture
【摘要】 目的 :探讨89Sr(锶 )治疗骨质疏松性骨折及其引起顽固性疼痛的疗效。方法 :对12例骨质疏松性骨折患者静脉注射89Sr,比较治疗前后患者疼痛程度及骨质量 (BMD)的改变 ,并与对照组比较。结果 :静脉注射 89Sr5~10天后 ,11例疼痛完全缓解(Ⅰ级) ,1例明显好转、仅轻度疼痛(Ⅱ级) ,总有效率100 %。治疗前后腰椎BMD百分率变化:显效4例 ,有效5例 ,无效3例 ,总有效率75 %。与对照组比较效果明显(P<0.05)。结论 :静脉注射 89Sr能有效治疗骨质疏松性骨折及其引起的顽固性疼痛。
【Abstract】 Objective:To explore the curative effect of strontium-89(89Sr)for treating osteoporotic fracture and refractory soreness caused by this disease.Methods:12 patients with osteoporotic fracture were given 89Sr by intravenous injection.The degree of pain and change of BMD were compared before and after treatment,and also compared with those in the control group.Results:In 5~10 days after 89Sr injection,the soreness relieved completely in 11 cases(grade Ⅰ),the patient was obvious on the mend in 1 case,with a little pain(grade Ⅱ).The total effective rate was 100%.The percentage of BMD was changed before and after treatment:4 cases were notable curetive effect,5 cases were effective,3 cases were ineffective,The total effective rate was 75%.Conclusion:89Sr intravenous injection can effectively treat the osteoporotic fracture and refractory soreness caused by this disease.
- 【文献出处】 现代医药卫生 ,Modern Medicine Health , 编辑部邮箱 ,2004年23期
- 【分类号】R817.4
- 【被引频次】2
- 【下载频次】64