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灵芝总甙对神经细胞损伤保护机制的研究
Protective effect of lingzhizongdai against nerve cell damnification
【摘要】 目的 :探讨灵芝总甙对小鼠神经细胞脑缺血样损伤模型的保护作用及其机制。方法 :采用组织培养法 ,以小鼠大脑皮层神经细胞为材料 ,制备缺血损伤模型。结果 :形态学检验发现灵芝总甙对脑缺血样损伤模型中的小鼠神经细胞具有明显保护作用 ,结晶紫染色也提示可显著提高损伤模型中神经细胞的存活数。结论 :灵芝总甙对小鼠神经细胞缺血损伤均有显著的保护作用。
【Abstract】 Objective:To observe the protective effect and mechanism of lingzhizongdai anainst murine model of ischemia injury.Methods:By using tissue culture of cortex neuron,the nurine model of ischemia injury was prepared.Results:It was found that lingzhizongdai possessed obvious protective effects on primary neurons in injury models by the way of morphological examination.Crystal violet staining also indicated that it increased number of life neurons in injury models significantly.Conclusion:Lingzhizongdai protected murine cortex cells from all injury models effectively in vitro.
- 【文献出处】 现代医药卫生 ,Modern Medicine Health , 编辑部邮箱 ,2004年16期
- 【分类号】R285
- 【被引频次】6
- 【下载频次】97