【摘要】 目的 :探讨内皮素 (ET)、肾素 (PRA)、血管紧张素Ⅱ (ATⅡ )、醛固酮(ALD)与肝硬化的相关性。方法 :测定41例肝硬化患者 ,其中肝功能Child -pughA级22例 ,B级19例 ,血浆ET、PRA、ATⅡ、ALD并与对照组进行比较。结果 :肝硬化组血浆ET、PRA、ATⅡ、ALD明显高于正常对照组 ,在肝功能Child -pugh分级中 ,ET、ALD、ATⅡ值B级>A级。结论 :ET、PRA、ATⅡ、ALD均与肝硬化形成有关 ,而ET、ALD、ATⅡ在肝硬化进展中尤为密切更多还原

【Abstract】 Objective:To explore the revelation of serum endothelin(ET),renin(PRA),angiotensin(ATⅢ),adosterone(ALD)level and cirrhosis.Methods:There were forty-one cirrhosis patients twenty-two patients in Child-pugh A Group(A Group)and nineteen patients in Child-pugh B(B Group),and serum ET,PRA,ATⅡand ALD levels were measured.Results:Serum ET,PRA,ATⅡand ALD levels in cirˉrhosis group were higher significantly than those in Control(P<0.05).The value of serum ET,ALD ATⅡlevels in Child-pugh B Group were higher than those in Child-pugh A Group(P<0.05).Conclusion:There were positive significantly revelations between serum ET,PRA,ATⅡlevels and formation of cirrhosis,furthermore,more positive revelation between serum ET,ALD,ATⅡlevels and the development of Cirrhosis.更多还原