【摘要】 利用635个包含完整转座因子插入的粳稻CDS序列,对转座因子如何影响基因编码区的碱基组成及基因的表达水平,进而对基因同义密码子的使用偏性产生影响进行了详细分析。结果表明:转座因子插入极显著地影响到基因编码区的同义密码子使用但并非唯一因素;转座因子对不同基因的表达水平具有多重影响,有的基因表达被抑制,有的反而增强,但总的来说它减少了基因表达水平对同义密码子使用的影响程度。更多还原

【Abstract】 By using 635 CDSs containing integral transposable element sequence (TEs), a detailed analysis on how the insertion of TEs affects gene nucleotide composition in coding region and gene expression level, and furthermore affects the synonymous codon usage bias in every genes was made. The results showed that the nucleotide composition in coding region of gene was significantly affected by the insertion of TEs, but that was not the only factor in yielding mutational bias. There existed multiple effects on the expression level of different genes, for example, the expression of some genes decreased, but others maybe enhanced. Overall, the effect of gene expression level on synonymous codon usage bias was decreased by the insertion of TEs.更多还原