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床旁B型利钠肽测定在急性呼吸困难鉴别诊断中的应用

APPLIED RESEARCH OF BED-SIDE B TYPE NATRIURETIC PEPTIDE ASSAYS IN DIFFERENTIATING ACUTE DYSPNEA

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【作者】 王如兴李肖蓉邵力正羊镇宇肖春晖王强杨光敏

【Author】 Wang Ruxing,Li Xiaorong,Shao Lizheng,et al.Department of Cardiology,First People’s Hospital of Wuxi City,Wuxi 214002,China

【机构】 江苏省无锡市第一人民医院心内科江苏省无锡市第一人民医院心内科 214002214002

【摘要】 目的探讨床旁B型利钠肽(BNP)测定对急性呼吸困难鉴别诊断的敏感性、特异性和准确性。方法采用美国博适-Triage干式快速定量心力衰竭/心肌梗死诊断仪对351例心源性和非心源性呼吸困难患者床旁BNP测定。结果按纽约心脏病协会(NYHA)不同心功能分级患者BNP水平不同;BNP水平<60pg/ml患者基本可诊断为非心源性呼吸困难;BNP水平>100pg/ml但<500pg/ml患者需考虑可能为心源性呼吸困难;>500pg/ml患者基本可诊断为心源性呼吸困难。结论BNP水平高低是鉴别心源性和非心源性呼吸困难可靠的指标。

【Abstract】 Objective To investigate sensitivity,specialty and accuracy of B type natriuretic peptide (BNP) assays in differentiating cardiac and non-cardiac dyspnea. Methods BNP levels of 351 patients with cardiac or non-cardiac dyspnea were measured by Triage CHF/AMI analyzer made by American Biosite company. Results BNP levels were different in different cardiac function patients according to NYHA;When BNP level is less than 60pg/ml,non-cardiac dyspnea can be diagnosed;when BNP level is between 100pg/ml and 500pg/ml,cardiac dyspnea should be considered;when BNP level is more than 500pg/ml,cardiac dyspnea can be diagnosed in general condition. Conclusion BNP level is an effective way to identify cardiac and non-cardiac dyspnea.

【关键词】 B型利钠肽呼吸困难
【Key words】 B type natriuretic peptidedyspnea
  • 【文献出处】 中国心血管病研究杂志 ,Chinese Journal of Cardiouascular Review , 编辑部邮箱 ,2004年08期
  • 【分类号】R446.1
  • 【被引频次】4
  • 【下载频次】36
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