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床旁B型利钠肽测定在急性呼吸困难鉴别诊断中的应用
APPLIED RESEARCH OF BED-SIDE B TYPE NATRIURETIC PEPTIDE ASSAYS IN DIFFERENTIATING ACUTE DYSPNEA
【摘要】 目的探讨床旁B型利钠肽(BNP)测定对急性呼吸困难鉴别诊断的敏感性、特异性和准确性。方法采用美国博适-Triage干式快速定量心力衰竭/心肌梗死诊断仪对351例心源性和非心源性呼吸困难患者床旁BNP测定。结果按纽约心脏病协会(NYHA)不同心功能分级患者BNP水平不同;BNP水平<60pg/ml患者基本可诊断为非心源性呼吸困难;BNP水平>100pg/ml但<500pg/ml患者需考虑可能为心源性呼吸困难;>500pg/ml患者基本可诊断为心源性呼吸困难。结论BNP水平高低是鉴别心源性和非心源性呼吸困难可靠的指标。
【Abstract】 Objective To investigate sensitivity,specialty and accuracy of B type natriuretic peptide (BNP) assays in differentiating cardiac and non-cardiac dyspnea. Methods BNP levels of 351 patients with cardiac or non-cardiac dyspnea were measured by Triage CHF/AMI analyzer made by American Biosite company. Results BNP levels were different in different cardiac function patients according to NYHA;When BNP level is less than 60pg/ml,non-cardiac dyspnea can be diagnosed;when BNP level is between 100pg/ml and 500pg/ml,cardiac dyspnea should be considered;when BNP level is more than 500pg/ml,cardiac dyspnea can be diagnosed in general condition. Conclusion BNP level is an effective way to identify cardiac and non-cardiac dyspnea.
- 【文献出处】 中国心血管病研究杂志 ,Chinese Journal of Cardiouascular Review , 编辑部邮箱 ,2004年08期
- 【分类号】R446.1
- 【被引频次】4
- 【下载频次】36