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血清C-反应蛋白与冠状动脉病变

THE CORRELATION BETWEEN C - REACTIVE PROTIEN AND SEVERITY OF CORONARY ARTERY DISEASE

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【作者】 邓昌明黄晶刘地川殷跃辉

【Author】 Deng Changming, Huang Jing, Liu Dichuan, et al. Department of Cardiology, The Second College of Clinical Medicine, Chongqing Medical University, Chongqing 400010

【机构】 重庆医科大学第二临床学院心血管内科重庆医科大学第二临床学院心血管内科 400010重庆市400010重庆市

【摘要】 目的 探讨冠状动脉病变患者血清C-反应蛋白水平及其与冠状动脉病变严重程度的关系。方法 采用免疫浊度法测定冠状动脉造影证实的A型冠状动脉病变患者血清C-反应蛋白(CRP),与年龄和性别相匹配的冠状动脉造影证实的非冠状动脉病变患者进行比较。冠状动脉病变程度采用Gensini积分,将冠状动脉病变患者血清CRP与Gensini积分进行相关分析。结果 冠状动脉病变患者血清CRP明显升高,CRP与冠状动脉病变Gensini积分明显相关(r=0.637,P<0.01)。结论冠状动脉病变患者血清CRP明显升高,CRP水平可反映冠状动脉病变的严重程度。因此血清CRP可作为冠状动脉病变程度的参考指标之一。

【Abstract】 Objective To measure the level of serum C- reactive protien(CRP) and investigate the correlation between CRP and the severity of coronary artery disease. Methods The level of CRP was measured in patients with coronary artery disease and the relationship between level of serum CRP and Gensini score was analysed. Results Compared with age and sex- matched patients with non- coronary artery disease, the level of CRP was significantly elevated in patients with coronary artery disease, and it was related to Gensini scores(r = 0.637, P<0.01) . Conclusion The level of CRP is elevated in patients with coronary artery disease, CRP reflect the severity of coronary artery disease, our results suggest that CRP is the candidator of coronary artery disease.

  • 【文献出处】 中国心血管病研究杂志 ,Chinese Journal of Cardiouascular Review , 编辑部邮箱 ,2004年01期
  • 【分类号】R541.4
  • 【被引频次】10
  • 【下载频次】62
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