【摘要】 目的:探讨小剂量甲状腺素治疗顽固性心功能不全的疗效。方法:26例经2周常规治疗效果不佳者作为治疗组,同期随机未予以甲状腺素治疗者19例为对照组,治疗组加甲状腺素20mg 1次/日,口服1月,观察、随访治疗前、后心功能、心脏射血分数(EF)、左室短轴缩短率(FS)、左室舒张期内径(LVDd)和血T3值的变化。结果:治疗组治疗后心功能明显改善,心脏射血分数增加,左室内径缩小(P<0.01),与对照组比较具有显著性差异(P<0.05),治疗组在治疗期间无不良反应发生。结论:小剂量甲状腺素治疗顽固性心功能不全是可取的。更多还原

【Abstract】 Objective: To investigate the effect of thyroxine on patients with intractable heart insufficiency. Methods: The 45 patients with intractable, chronic heart insufficiency were randomly divided into 2 group, 29 cases of observation group and 19 cases of control group. All of them were received routine treatment, the group of observation received thyroxine (20mg/d oral, for one mouth) also. The cardiac function degree (NYHA) , Cardiac ejection fraction (EF), FS, Left ventricular diastolic internal diameters (LVDd) and value of T3 were measured before and after treatment. Results:The value of EF, FS, T3 and function were notably improved and the value of LVDd was notably descended as compared with those of the control group (P<0. 05). There were no significant side-effects in observation group in period of treatment. Conclusion: Low dose thyroxin can be used to treat the chronic and intractable heart insufficiency.更多还原