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自体角膜缘干细胞移植术治疗翼状胬肉43例临床观察

Clinical Observation of Corneal Limbal Stem Cell Autograft Transplantation in Treatment of Pterygium

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【作者】 舒强林汉云张劲

【Author】 SHU Qiang,LING Han-Yun,ZHANG Jin (Department of Ophthalmology,The First Hospital of Huangshi,Huangshi Hubei 435000 China)

【机构】 黄石市第一人民医院眼科黄石市第一人民医院眼科 湖北黄石435000湖北黄石435000湖北黄石435000

【摘要】 目的评价自体角膜缘干细胞移植术治疗翼状胬肉的疗效。方法采用自体角膜缘干细胞移植术治疗5 4眼 (4 3例 )翼状胬肉 ,其中原发性翼状胬肉 38眼 ,复发性翼状胬肉 16眼。 16眼复发性胬肉均经过两次以上的单纯胬肉切除术或结膜下转移术。结果术后随访 6 - 18个月 ,无术后并发症发生。 4 9眼无胬肉组织再生 ,5眼在术后 8- 11个月复发 ,复发率为 9.3%。结论自体角膜缘干细胞移植术能为受损的角膜缘提供新的干细胞 ,是一种安全、有应用前景的治疗翼状胬肉的手术方式。

【Abstract】 Objective To assess the therapeutic effects of corneal limbal stem cell autograft transplantation for the treatment of pterygium. Methods Corneal limbal stem cell autograft transplantation were performed on 54 eyes(43 cases) with newly developed(n=38) or recurrent pterygium(n=16). All the recurrent pterygium had already been treated at least twice either by simple excision (n=11) or by conjunctival rotation autograft (n=5).Results During 6-18 months of follow-up no postoperative complications occurred. In 49 eyes no pterygium recurrence was recorded; recurrence occurred in 5 eyes (9.3%) after 8 to 11 months. Conclusion Corneal limbal stem cell autograft transplantation can provide new stem cells for the damaged limbal,it seems to be a promising and safe procedure for pterygium.

【关键词】 角膜缘干细胞自体移植翼状胬肉
【Key words】 Corneal limbal stem cellAutograftPterygium
  • 【文献出处】 咸宁学院学报(医学版) ,Journal of Xianning College(Medical Sciences) , 编辑部邮箱 ,2004年02期
  • 【分类号】R779.6
  • 【被引频次】1
  • 【下载频次】11
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