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氟马西尼在小儿麻醉中的应用

The Clinical Evaluation of Flumazenil in Pediatric Anesthesia

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【作者】 曾香云胡啸玲

【Author】 ZENG Xiang-yun, HU Xiao-ling (Department of Anaesthesia, People’s Hospital of Qidong County, Qidong 421600, Hunan, China)

【机构】 湖南省祁东县人民医院麻醉科湖南省南华大学附一院麻醉科 祁东421600衡阳421001

【摘要】 目的 探讨氟马西尼应用于小儿麻醉后催醒的临床效果。 方法 选择 5 0例施行疝囊高位结扎术的患儿 ,随机分为 2组 :Ⅰ组术后静脉推注氟马西尼 8μg/kg催醒 ,Ⅱ组则不予氟马西尼催醒。 结果 术后苏醒时间比较 ,Ⅰ组为 (5 .6± 0 .6 )min ,较Ⅱ组的 (4 6 .7± 8.4 )min明显缩短 (P <0 .0 5 ) ;催醒后烦躁、谵妄的发生率 ,醒后 5min之内Ⅰ组较Ⅱ组高 ,但 5min之后两组间无统计学差异。 结论 氟马西尼用于小儿麻醉后催醒可以明显缩短患儿的苏醒时间 ,且安全可行。

【Abstract】 Objective To observe the effects of flumazenil in pediatric anesthesia. Methods 50 children underwent high ligation of hernial sac with total intravenous anesthesia (TIVA) were randomized into 2 groups. Group Ⅰwas given flumazenil 8μg/kg after operation, compared with group Ⅱwith no flumazenil administration after operation. Results The recovering time in groupⅠwas shorter than which in group Ⅱ(5.6±0.6 min vs 46.7±8.4 min, P<0.05). The rates of dysphoric and delirium in group Ⅰ were higher than those of group Ⅱ during 5 minutes after aweakness, but there was no significant difference 5 minutes later. Conclusion Flumazenil is safe to reduce recovering time after TIVA in clildren.

【关键词】 麻醉氟马西尼儿童
【Key words】 anesthesiaflamazenilchild
  • 【文献出处】 中国现代手术学杂志 ,Chinese Journal of Modern Operative Surgery , 编辑部邮箱 ,2004年02期
  • 【分类号】R726.14
  • 【被引频次】1
  • 【下载频次】83
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