【摘要】 目的:评价自动输氧器(静舒氧)对急性脑梗死的治疗作用,观察静舒氧对患者血液黏稠度和神经功能的改善作用。方法:选择广州市第一人民医院脑系内科2003-10/2004-06收治的168例无严重心、肺、肝、肾损害的急性脑梗死患者,按肌力≤3级和肌力>3级分为轻症及重症两类,并随机编入对照组和治疗组,两组均常规治疗配合康复训练,治疗组加用自动输氧器(静舒氧)治疗,250mL/次,1次/d,10d为1个疗程,使用一两个疗程;治疗前后监测血液黏稠度并进行神经功能缺损(改良SSS)评分,以评判疗效。结果:血液黏稠度与病情严重程度无关;两组患者血液黏稠度前后比较差异有非常显著性意义(P<0.01),治疗组优于对照组(P<0.05);改良SSS评分治疗组重症患者治疗前为28.9±7.0,治疗后为16.0±4.0,轻症患者治疗前为8.8±4.3,治疗后为3.6±3.4,对照组重症患者治疗前为26.9±6.6,治疗后为19.9±7.2,轻症患者治疗前为9.0±4.4,治疗后为4.8±3.2,各组治疗前后比较差异均有非常显著性意义(t=7.602～11.004,P<0.01),治疗组优于对照组(t=-2.525～-2.343,P<0.05)。结论:自动输氧器(静舒氧)对提高急性脑梗死治愈率有帮助作用,且经济、方便、安全。更多还原

【Abstract】 AIM:To assess the therapeutic effect of auto oxygen insufflation apparatus(Jing Shu Yang)for treatment of acute cerebral infarction(ACI)and observe the role of Jing Shu Yang in improving the viscosity and neurological impairment of ACI patients. METHODS:Totally 168 patients with ACI who had no severe damage of heart,lung,liver and kidney, were selected from the Department of Brain Internal Medicine,the First People’s Hospital of Guangzhou from October 2003 to June 2004. The patients were assigned into mild cases(muscle strength ≤grade 3) and severe cases(muscle strength > grade 3) according to the muscle strength, and then randomized into control group and treatment group.Rehabilitation therapy was performed in the two groups,but Jing Shu Yang only in the treatment group(250 mL per time,once a day,ten days as a course,successively for 1-2 courses).Blood viscosity was monitored and neurological impairment was scored with modified SSS scale to evaluate the therapeutic effect. RESULTS:Blood viscosity had no relation with severity of disease. There were very significance differences in the two groups before and after treatment separately(P< 0.01),and the effect in the treatment group was prior to that in the control group after treatment(P< 0.05).In the treatment group, the scores of modified SSS before and after treatment were 28.9±7.0 and 16.0±4.0 for the severe cases respectively,and 8.8±4.3 and 3.6±3.4 for the mild cases.In the control group, the scores of modified SSS before and after treatment were 26.9±6.6 and 19.9±7.2 respectively for the severe cases, and 9.0 ±4.4 and 4.8±3.2 for the mild cases.There were very significant differences in the SSS scores of each group before and after treatment(t=7.602 to 11.004,P< 0.01).The scores of SSS in the treatment group was better compared with the control group (t=-2.525 to -2.343,P< 0.05). CONCLUSION:Auto oxygen insufflation apparatus,which is economic,comfortable and safe, is of benefit to improving the cure rate of ACI.更多还原