【摘要】 目的:探讨针刺治疗变异型心绞痛的疗效及其对血管内皮系统功能的影响。方法:变异型心绞痛患者62例,按随机数字表法分为针刺组(32例)和对照组(30例),分别予以硝酸盐、钙离子拮抗剂和阿司匹林治疗4周,针刺组在西药基础上加针刺内关、三阴交、足三里、心俞、太冲、神门。结果:针刺组:显效24例,有效6例,无效2例;对照组:显效20例,有效5例,无效5例;针刺组:疗效明显优于对照组(χ2=95.38,P<0.05)。针刺组治疗后,血浆一氧化氮为(86.92±23.15)μmol/L,较治疗前犤(63.78±22.07)μmol/L犦明显升高,差异有显著性意义(t=2.925,P<0.01)。针刺组治疗后一氧化氮较对照组明显升高(t=17.785,P<0.05)。结论:针刺辅助治疗变异型心绞痛能明显改善临床症状,提高血浆一氧化氮水平,改善血管内皮系统功能。更多还原

【Abstract】 AIM:To explore the efficacy of acupuncture in treating variant angina pectoris and its effect on the function of vascular endothelial system. METHODS:Sixty-two patients with variant angina pectoris were randomly divided into acupuncture group (n=32) and control group (n=30).All the patients were tr eated with 5-isosorbide mononitrate,diltiazm hydrochloride and aspirin respecti vely for 4 weeks, besides,patients in the acupuncture group received acupuncture treatment at the appoints of neiguan,sanyinjiao,zusanli,xinyu,taichong and shen men. RESULTS: There were 24 cases with significant effect, 6 with effect and 2 with out effect in the acupuncture group, while those in the control group were 20, 5 and 5 cases respectively. The curative effect of the acupuncture group was sign ificantly better than that of the control group (χ2=95.38,P< 0.05). Plasma nitr ic oxide after treatment in the acupuncture group was (86.92±23.15) μmol/L, si gnificantly increased compared with before treatment [(63.78±22.07)μmol/L] (t= 2.925,P< 0.01), also obviously higher than that in the control group (t=17.785, P< 0.05). CONCLUSION:Acupuncture treatment can obviously improve clinical symptoms of va riant angina pectoris, increase plasma nitric oxide level and ameliorate the fun ction of vascular endothelial system.更多还原