【摘要】 目的:观察脑损伤后颅内血肿患者的记忆障碍特征,并进行随访研究。方法:82例脑损伤后颅内血肿患者发病后1,6个月分别接受修订后的韦氏记忆量表(Wechslermemoryscale,WMS)评估,并与79例正常人对照。结果:脑损伤颅内血肿患者发病后1个月时的长时记忆、短时记忆、瞬时记忆的各项分测验评分以及记忆商值均明显低于对照组(t=2.058～4.275,P<0.01～0.05)。脑损伤颅内血肿患者发病6个月时的WMS测评中,顺数10.9±2.6,倒数12.5±3.4,累加10.8±2.7,再认11.0±2.5,视觉再生10.2±2.8,联想学习10.7±2.4,触觉记忆9.6±2.0,逻辑记忆10.2±2.8,背数10.5±2.5等分测验和记忆商值106.4±24.7均明显优于发病1个月时各项测评值(t=2.073～3.468,P<0.05～0.01)。脑损伤颅内血肿患者一般情况和临床特征分与记忆商值比较中,男性、≥55岁、昏迷≥1h、血肿体积≥20mL、多个血肿、硬膜下和急性硬膜下血肿各组的记忆商值均明显低于女性、<55岁、昏迷<1h、血肿体积<20mL、单个血肿、硬膜外和慢性硬膜下血肿(t=2.137～3.421,P<0.01～0.05)。结论:脑损伤颅内血肿患者的记忆功能受到明显损害,但在发病后6个月时可得到显著改善。记忆功能损害与年龄、性别、昏迷时间、血肿体积、位置、个数以及形成速度密切相关。更多还原

【Abstract】 AIM:To explore the characteristics of memory disorder in the patients with intracranial hematoma(IH) after brain injury(BI) and to perform a follow up. METHOD:One and six months after BI,82 IH patients(BI group) were inquired by Wechsler Memory scale(WMS), espectively,and the results were compared with those of the normal subjects(control group). RESULTS:One month after BI,the scores of WMS in long term memoy, short term memory,immediate memory and,memory quotient(MQ) in the BI group were obviously lower than those in the control group(t=2.058-4.275;P< 0.01-0.05).Six months after BI, the scores of WMS in counting from 1-100(10.9±2.6),100-1(12.5±3.4),addition (10.8±2.7), card recall(11.0±2.5), recognition(10.2±2.8), association(10.7±2.4),tactile memory(9.6±2.0), comprehension(10.5±2.5), and MQ (106.4±24.7) were all better than those of the patients just one month after BI(t=2.073-3.468,P< 0.01-0.05).Comparing the general condition and clinical characteristics with MQ,the results were better in the male patients who aged≥55 years,in a state of unconsciousness≥1 hour,with hematoma volume≥20 mL,multiple hematoma,subdural edema and acute subdural edema than the female patients who aged < 55 years in a state of unconsciousness for less than 1 hour,with hematoma volume≥20 mL,single hematoma, epidural edema and chronic subdural edema(t=2.317-3.421;P< 0.01-0.05). CONCLUSION:It is suggested that memory function in the patients with IH is seriously damaged,but it is improved 6 months after BI.Memory disorder is closely associated with age,gender,unconscious time,hematoma volume,site,amount,and speed that the hematoma forms.更多还原