【摘要】 目的:观察巴氯酚(Baclofen)结合康复治疗对脑卒中痉挛性偏瘫患者关节活动度、运动功能和ADL等方面的影响。方法:对144例脑卒中痉挛性偏瘫患者,随机分为治疗组和对照组。治疗组84例,服用巴氯酚结合康复治疗;对照组60例,只接受康复治疗。在治疗前和治疗后12周分别进行Ashworth,FMA和MBI量表评定以观察疗效。结果:治疗后Ashworth评定治疗组显效率为67.86%(上肢),63.60%(下肢),有效率为86.90%(上肢),89.29%(下肢);对照组显效率为41.60%(上肢),45.00%(下肢),有效率为76.67%(上肢),78.33%(下肢)。两组患者关节活动度、运动功能和生活能力均有明显改善(P<0.01),但治疗组明显优于对照组(P<0.05)。结论:巴氯酚结合康复治疗能明显改善脑卒中偏瘫肢体的痉挛状态,提高患者的关节活动度、运动功能和生活能力。更多还原

【Abstract】 AIM:To observe curative effects of baclofen combined with rehabilitation training on motion range of joint,motor function and ability of daily living(ADL) in the stroke patients with spastic hemiplegia. METHODS:Totally 144 stroke patients with spastic paralysis were randomly divided into two groups. Treatment group(n=84) received baclofen and rehabilitation therapy, and control group(n=60) only received rehabilitation therapy. Scores of Ashworth,Fugl Meyer assessment(FMA) and modified Barthel index(MBI) were recorded before treatment and 12 weeks after treatment. RESULTS:After treatment, Ashworth evaluation revealed that fair in 67.8%upper limbs and 63.60%lower limbs,improvement in 86.90%upper limbs and 89.29%lower limbs for the treatment group,while fair in 41.60%upper limbs and 54.00%lower limbs,improvement in 76.67%upper limbs and 78.33%lower limbs.Both groups have remarkable improvement in motion range of joint,motor function and ADL(P< 0.01),but the scores of the treatment group were significantly superior to those of the control group(P< 0.05). CONCLUSION:Baclofen combined with rehabilitation therapy can effectively relieve spasticity and improve the motion range of joint,motor function and ADL of the stroke patients with spastic hemiplegia.更多还原