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尿微量蛋白在肾病中的变化及意义

Changes of uric microprotein in nephropathy and its significance

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【作者】 张丁丁袁有才钟亚玲游正芸黄文方杜琼赖德明

【Author】 ZHANG Ding-ding 1, YUAN You-cai 2, ZHONG Ya-ling 1, YOU Zheng-yun 1, HUANG Wen-fang 1, DU Qiong 1, LAI De-ming 1 (1. The People’s Hospital of Sichuan Province, Chendu 610072, Sichuan, China; 2. The Second Hospital of Neijiang, Neijiang 641000, Sichuan, China)

【机构】 四川省人民医院四川省内江市第二人民医院四川省人民医院 四川成都610072四川内江641000四川成都610072四川成都610072

【摘要】 目的 探讨尿微量蛋白在肾病中的变化及临床意义。方法 采用速率散射比浊法检测 196例肾病患者尿微量蛋白水平。结果 肾病患者尿微量白蛋白 (MA)、转铁蛋白(TRF)、α1-微球蛋白 (α1-MG) ,免疫球蛋白G(IgG)水平均显著高于对照组 (P <0 .0 1) ,8种原发性、继发性肾病患者尿微量白蛋白水平显著高于对照组 ,尿素氮 (BUN)、肌酐 (Cr)异常的肾病患者 ,其尿微量白蛋白含量与BUN ,Cr呈显著正相关 (P均 <0 .0 5 )。结论 尿微量蛋白与肾脏病变密切相关 ,尿微量白蛋白可作为判断肾脏病变的良好指标

【Abstract】 Objective It is to discuss the changes of uric microprotein in nephropathy and its clinical significance.Methods The levels of uric microprotein in 196 nephropathy patients were measured with speed scatter nephelometer.Results The levels of uric microprotein in nephropathy patients were significantly higher than those in control group (P<0.01). The levels of uric microalbumin in 8 dinds of primary and secondary nephropathy patients were significantly higher than those in control group. The contents of uric microalbumin in the patients whose blood urea nitrogen (BUN) and creatinine (Cr) were abnormal were correlated positively with BUN and Cr (P<0.05).Conclusion There is closely related between the levels of uric microprotein and nephropathy. Uric microalbumin may be used as a nicer index of nephropathy.

【关键词】 尿微量蛋白肾病尿素氮肌酐
【Key words】 uric microproteinnephropathyblood urea nitrogencreatinine
  • 【文献出处】 现代中西医结合杂志 ,Modern Jorunal of Integrated Traditional Chinese and Western Medicine , 编辑部邮箱 ,2004年13期
  • 【分类号】R692
  • 【被引频次】4
  • 【下载频次】104
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