【摘要】 综述了20世纪90年代以来以杂环物质衍生物、β酮酯类化合物及其他化合物为原料合成5-氨基乙酰丙酸(ALA)的研究进展。评述了以糠胺、四氢糠胺、5-羟甲基-2-糠醛、乙酰丙酸、丁二酸单乙酯酰氯、单甲酯丁二酸和甘氨酸为原料的合成方法以及部分合成方法的优缺点及工业应用前景。介绍了 ALA 在农业领域作为无公害绿色除草剂、杀虫剂、落叶剂、植物生长调节剂等的应用,及其在医学领域和有机合成中的应用。更多还原

【Abstract】 Different procedures for the synthesis of 5-aminolevulinic acid(ALA)since nineties,20th century are reviewed, which were divided into three aspects containing heterocyclic compounds,β-keto esters and other reactants.Furfurylamine,te- trahydrofurfurylamine,5-hydroxymethyl furfural,levuinic acid,ethyl succinyl chloride,monomethyl malonic acid and glycine are mainly described,among which advantages,disadvantages and possibilities of industrialization are summarized.ALA is known to have prospective applications in herbicides,insecticides,defoliants and growth regulators.Also the applications of ALA in agri- culture,medicine and organic synthesis are introduced.更多还原