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高效液相色谱控制三黄片生产质量的研究
Application of HPLC Chromatogram to Quality Control for Sanhu ang Tablet
【摘要】 目的 :利用 HPL C色谱图对照法控制三黄片的质量和生产工艺。方法 :制备三黄片半成品、成品、对照品的 HPL C色谱图 ,测算大黄素、大黄酚总量 ,比较色谱图的共有峰和异常色谱峰。结果 :该法能有效控制三黄片含量和生产工艺。结论 :HPL C色谱图对照法可作为三黄片生产过程中质量监控的手段。
【Abstract】 Objective:To control production and quality of San Huang Tablet by HPLC.Methods:Prepared HPLC chromatograms of San Huang Tablet’s semi-manufactured goods, finished product and contrast chromatogram;Calculated g ross of emodin and chrysophanol;Compared characteristic and abnormity peaks.Results:The method can control assay of San Huang Tablet,a nd monitor manufacture’s course.Conclusion:To compare HPLC chromatograms is an important q uality control’s means in San Huang Tablet’s manufacture course.
- 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,2004年12期
- 【分类号】TQ461
- 【被引频次】2
- 【下载频次】204