【摘要】 目的　探讨前列地尔对肺心病并发多脏器衰竭 (MOF)的疗效。方法　对 70例患者随机分为A组 40例 (观察组 ) ,选用前列地尔注射液 1 0～ 2 0 μg ,另给氨茶碱 0 .2 5～ 0 .5g,加 50 %葡萄糖液 2 0～ 40ml静注 ,1 /d ,疗程 2W。B组不予前列地尔治疗 ,其余治疗同A组。观察血气 (PO2 、PCO2 )、BUN、Cr、CI、EF、神志、呕血、便血 ,基础情况治疗后A、B两组的变化。结果　A组的显效率及有效率明显高于B组 (P <0 .0 1 ) ,基础情况治疗后A组疗效明显优于B组 (P <0 .0 1 ) ,但B组间比较无明显改变 (P >0 .0 5)。结论　前列地尔与氨茶碱合用对肺心病并发多脏器衰竭的疗效显著优于单独使用氨茶碱。更多还原

【Abstract】 Objective To explore the curative effect of alprostadil on patients with pneumocarditis complicated with MOF. Methods Seventy patients with cor pulmonale complicated with MOF were divided into two groups randomly. Fourty patients were selected as group A (experimental group), treated with Alprosstadil and Aminophylline for two weeks. The treatment of group B was the same as group A except alprostadil. Blood gas analysis, blood urea nitrogen (BUN), creatinine (Cr), cardiac output (CI), ejection fraction (EF), consciousness, hematemesis and hematochezia were compared between group A and group B after treatment. Results Effective rate of group A was higher than that of group B (P<0.01). Conclusions The curative effect of Alprostadil and Aminophylline on patients with pneumocarditis complicated with MOF was better than using aminophylline only.更多还原