【摘要】 目的　探讨儿童甲状腺功能亢进症 (甲亢 )的药物治疗和手术治疗效果。方法　药物治疗组予丙硫氧嘧啶或甲硫咪唑口服 ,持续 1.5～ 2年 ;手术治疗组采用甲状腺次全切除术。比较两种治疗方法的治疗效果。结果　药物治疗组 0 .5年有效率为 60 % ,1年有效率 70 % ,停药 2年复发率 40 % ,治愈率 60 % ;手术治疗组平均住院 16d ,无神经损伤、甲状旁腺功能减退、甲状腺危象及甲状腺功能减退等并发症 ;术后随访 2年 ,治愈率10 0 % ,生长发育正常。结论　药物治疗无效、停药后复发或不能坚持长期服药、中重度甲亢和有压迫症状者可手术治疗。甲状腺次全切除术治疗儿童甲亢疗效迅速、确切、安全 ,不影响生长发育更多还原

【Abstract】 Objective To evaluate the effect of medicial and surgical treatment for juvenile hyperthyroidism.Methods Ortapazole was administ rated separately in drug therapy group for 1.5-2 years.Bilateral subtotal thyroidectomy was done in surgical therapy group.Results In drug therapy group,effective rate was 60 percent in 6 months and 70 percent in one year.Recurrence rate was 40 percent after drug withdrawal in 2 years curative rate was 60 percent.In surgical therapy group,the average stay in hospital was 16 days.There was no nerve injury,parathyroidal hypofunction,thyroid crisis or hypothyroidism complications,with 100 percent curative rate after 2 years′ followup.Postoperative growth and development were normal.Conclusions Surgical treatment may be suitable for those who have no response to drug therapy,with recurrence after drug withdrawal,whose compression symptom was obvious,with moderate and severe hyperthyroidism or those who could not take medicine persistently.Bilateral subtotal thyroidectomy applied in juvenile hyperthyroidism could achieve quick and better recovery,and has no influence on the juvenile growth and development.更多还原