【摘要】 目的　分析足月新生儿缺氧缺血性脑病 (HIE)的CT表现特点及其预后情况。方法　对 2 68例临床诊断为HIE的患儿进行CT检查 ,分析其CT表现。 74例行 1～ 4次CT复查。 19例正常新生儿作为对照组。结果　 2 13例有异常CT表现 ,占 79%。其中 ,脑白质低密度区CT值 <18HU者 2 0 0例 ,占 94% ,低密度区范围扩大者 192例 ,占 90 %。蛛网膜下腔出血 7例 ,占 3 .3 %。脑室内出血 4例 ,约占 2 %。脑梗塞 1例 ,约占 0 .5 %。 1月～ 1岁左右复查 5 1例 ,其中 2 7例CT有异常表现 ,轻、中度主要表现为外部性脑积水 ,重度主要表现为脑软化灶 ,脑萎缩。 2岁以后复查 2 3例 ,有 2例表现为外部性脑积水 ,1例表现为脑萎缩。结论　HIE的CT表现主要为 :①脑水肿 ,表现为脑白质出现低密度区 ,该低密度区CT值更小 (一般 <18HU) ,范围更大 ;②脑出血 ,主要为蛛网膜下腔出血及脑室内出血 ;③脑梗塞 ,少见。轻、中度HIE患儿预后较好 ,重度HIE患儿预后差更多还原

【Abstract】 Objective To study CT findings and prognosis of hypoxic -ischemic encephalopathy in full term neonates .Methods Two hundred and sixty-eight cases of full-term neonates diagnosed clinically as hypoxic-ischemic enceohathy(HIE) were examined.Seventy-nine cases were observed by CT follow-up one or four times.Nineteen normal neonates with same age were selected as contral group.Results Two hundred and thirteen cases(79%)were abnormal on CT.The CT value of the low density area of brain white matter were lower than 18 HU in two hundred cases(94%).The low density area were enlarged in one hundred and ninty two cases(90%).Subarachnoid hemorrhage(SAH) were found in seven cases(3.3%) and intraventricular hemorrhage(IVH) in four cases(2%), and infarction in one case (0.5%).CT follow-up study of 51 cases were carried out around one year of age . 27 of them were abnormal on CT,mostly showing external hydrocephalus,minority of them with cerebral atrophy and softening .23 cases were studied by CT follow-up at or after two years old,3 of them had external hydrocephalus and 1 of them had cerebral softening.Conclusion CT findings of HIE mostly had :①brain edema showing lower density area of enlarged brain white matter;②brain hemorrhage mostly showing subarachnoid hemorrhage and intraventricular hemorrhage;③seldom brain infarction.Prognosis of HIE which was mild and moderate degree based on CT findings was better ,and severe degree was bad.更多还原