【摘要】 目的　探讨康莱特联合术前新辅助化疗对ⅢA期非小细胞肺癌手术后并发症的影响。方法　1999年 1月至 2 0 0 3年 12月对 4 7例ⅢA期非小细胞肺癌患者行康莱特联合新辅助化疗 ,选择同期 4 5例单用新辅助化疗的患者作对照 ,所有病例均行肺叶或全肺切除术加纵隔淋巴结清扫术 ,以术后总引流液量、术后肺部感染、需行药物治疗的心律失常、肺不张需行纤支镜吸痰、支气管胸膜瘘、肺水肿和肺栓塞作为术后并发症的观察指标 ,比较术后死亡率。结果　康莱特联合术前新辅助化疗的病例术后总引流液量 ,肺部感染发生率、需行药物治疗的心律失常发生率明显小于单用新辅助化疗的病例 (P <0 .0 5 ) ,单用新辅助化疗的病例中有 3例术后死亡。结论　康莱特联合新辅助化疗可减少ⅢA期非小细胞肺癌术后并发症发生率 ,降低术后死亡率。更多还原

【Abstract】 Object To analyze the postoperative complications of stage IIIA non-small cell lung cancer (NSCLC) treated with Kong LaiTe Injection combining preoperative neoadjuvant chemotherapy.Methods Forty-seven patients with stage IIIA NSCLC received Kong LaiTe Injection combining neoadjuvant chemotherapyfrom Jua. 1999 to Dec. 2003. Simultaneously 45 cases received single neoadjuvant chemotherapy comparatively. All the patients had partial or total pneumonectomy and celarance of diaphragmatic lymph node. The observing indicators are total drainage,postoperative pulmonary infection, cardiac arrhythmia needing drug treatment,non-expanded lung, pulmonary atelectasis needing sucking sputum by fiber-rami Brocho-endoscopy, bronchopleural fistula, pulmonary edema, pulmonary embolism.The postoperative mortality was compared. Result The occurring rates of postoperative drainage, pulmonary infectio, cardiac arrhythmia needing drug treatment for patients treated with Kong LaiTe Injection combining preoperative neoadjuvant chemotherapy are apparently smaller than those of patients treated with single neoadjuvant chemotherapy (P<0.05) . 3 patients died in the group of single neoadjuvant chemotherapy. Conclusion Kong LaiTe Injection combining neoadjuvant chemotherapy to treate Stage ⅢA non-small cell lung cancer can reduce the postoperative complications and mortality.更多还原