【摘要】 目的　了解鹿茸养生汤的毒理学安全性。方法　小鼠急性毒性试验和遗传毒性试验 (Ames试验、小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验 )。结果与结论　鹿茸养生汤的小鼠经口LD50 >2 0 g/kg ,为实际无毒级物质 ;在Ames试验、小鼠骨髓嗜多染红细胞微核试验和小鼠精子畸形试验中均呈阴性反应 ,未显示致突变作用 ,表明鹿茸养生汤基本无毒性和无致突变性。更多还原

【Abstract】 Objective To observe the toxicological safety of Lurong yangsheng decoction. Methods Acute toxicity tests and mutagenicity tests (Ames test,micronucleus test of bone marrow cell in mice and sperm shape abnormality test in mice)were chosen to evaluate. Results and Conclusion The results showed that LD 50 (per os) was higher than 20 g/kg, indicating that Lurong yangsheng decoction is non-toxic, and no significant difference have been found between each test group and the control group in mutagenicity tests, indicating that Lurong yangsheng decoction does not induce mutation.更多还原