【摘要】 [目的 ]观察米索前列醇预防高危妊娠产后出血的效果。 [方法 ]将98例有出血倾向的高危妊娠产妇随机分为试验组及对照组 ,试验组于胎儿娩出后口服米索前列醇 40 0 μg ,对照组于胎儿娩出后肌肉注射催产素2 0IU ,观察两组产后 2h内出血量等指标。 [结果 ]产后 2h平均出血量试验组为 180 .2 8ml± 2 5 .5 6ml,对照组为 2 97.3 3ml± 67.67ml,试验组产后出血量明显少于对照组 ,差异有统计学意义 (P <0 .0 5 )。 [结论 ]米索前列醇促进产后子宫收缩作用强于催产素 ,能较好地预防高危妊娠产妇产后出血 ,且用药方便、安全。更多还原

【Abstract】 Objective: to observe the effect of Misoprostol to prevent postpartum hemorrhage for high risk pregnant. Method: a total of 98 cases of high risk pregnant with bleeding tendency were randomly divided into both test group and control group. Patients in test group were given Misoprostol orally taken at a dose of 400 μg after delivery, while patients in control group were given Oxytocin at a dose of 20 IU by intramuscular injection after delivery. Indexes such as postpartum hemorrhage of patients within 2 hours after delivery were observed.Result: the average amounts of postpartum hemorrhage within 2 hours after delivery in test group were 180.20 ml±25.56 ml and 297.33 ml±67.67 ml in control group respectively. There was significant difference between the two groups. Patients of test group had less postpartum hemorrhage than that of control group patients had (P<0.05). Conclusion: the effect of Misoprostol on accelerating uterine contraction after delivery is superior to that of Oxytocin, which can prevent postpartum hemorrhage in high risk pregnant efficiently. It is also convenient and safe to use.更多还原