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蛋白质亚细胞定位的识别

THE RECOGNITION OF SUBCELLULAR LOCATION OF PROTEIN

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【作者】 李凤敏李前忠

【Author】 Li Feng-min1,2, Li Qian-zhong1(1. Department of Physics, College of Sciences and Technology,Inner Mongolia University, Hohhot 010021, China;2. Inner Mongolia Vocational College of Water Conservancy, Hohhot 010051, China)

【机构】 内蒙古大学理工学院物理系内蒙古大学理工学院物理系 呼和浩特010021内蒙古水利职工大学呼和浩特010051呼和浩特010021

【摘要】 根据蛋白质的亚细胞定位,将蛋白质分为12类,用离散量的数学理论,以蛋白质中400个氨基酸二联体数目构成离散源,通过计算离散增量预测蛋白质的亚细胞定位,用Self-consistency和Jackknife两种方法测试均获得较高的预测成功率。结果表明:Self-consistency方法预测成功率为84.5%,Jackknife方法预测成功率为81.1%。

【Abstract】 According to the subcellular location of a protein, proteins were classified into twelve groups. Based on the theory of measure of diversity, the sources of diversity were determined by the number of the adjacent residue-pair in the primary sequence of a protein. By calculating the increment of diversity, the subcellular location of a protein could be predicted. The high rates of correct prediction were obtained by Self-consistency test and Jackknife test. The predictive success rates of two tests were 84.5% and 81.1% respectively.

【基金】 国家自然科学基金项目(30160025)
  • 【文献出处】 生物物理学报 ,Acta Biophysica Sinica , 编辑部邮箱 ,2004年04期
  • 【分类号】Q51
  • 【被引频次】40
  • 【下载频次】711
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