【摘要】 微卫星DNA是广泛存在于各种真核生物基因组中的短串联重复序列,具有突变速率快、多态性高等特点,本文分析了微卫星的多态性及其形成机制,并简要介绍其在亲缘关系鉴定、种群遗传结构分析、基因图谱以及基因诊断等方面的应用。更多还原

【Abstract】 Microsatellite DNA, comprising short tandem repeated nucleotide sequences, is ubiquitous in eukaryotic genomes. It offers unusual advantages, such as abundant polymorphisms, rapid and convenient analysis. Here, the polymorphism mechanism of macrosatellite DNA is introduced and the latest application of microsatellite is reviewed, including its mutations, relationship identification, analysis of population genetics, microsatellite mapping and so on.更多还原