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清醒和麻醉状态下豚鼠畸变产物耳声发射检测比较

Research on DPOAE of Guinea Pigs under Awake and Anesthetic Conditions

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【作者】 叶林峰肖伯奎华清泉黄治物陶泽璋周绪红

【Author】 Ye Linfeng 1,2 Xiao Bokui 1 Hua Qingquan 1 Huang Zhiwu 1 Tao Zezhang 1 Zhou Xuhong 2 1 (Department of ENT-Head and Neck Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China) 2 (Department of ENT,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)

【机构】 武汉大学人民医院耳鼻咽喉-头颈外科武汉大学中南医院耳鼻咽喉科 武汉430060武汉大学中南医院耳鼻咽喉科武汉430071武汉430060武汉430071

【摘要】 为了观察豚鼠在麻醉和清醒状态的畸变产物耳声发射 (DPOAE)。我们以 DPOAE幅值和 I/ O曲线作为参数 ,观察清醒和麻醉状态下其参数的变化。结果发现豚鼠在清醒状态下其 DPOAE幅值和 I/ O曲线斜率与正常剂量麻醉状态下相比无显著性差异 (P>0 .0 5 )。我们认为在清醒状态下豚鼠 DPOAE的检测同麻醉状态相比 ,操作简便、结果稳定 ,更接近于生理状态。

【Abstract】 In order to observe the DPOAE of guinea pigs under awake and anesthetic conditions,we invesitigated the amplitude of distortion product emission and I/O function curves and made a comparative analysis of their changes under different conditions. It was found that the amplitude of DPOAE and I/O curves did not show difference in the guinea pigs under awake and anesthetics conditions.We deem it credible and simple to measure DPOAE in the guinea pigs under awake condition,which is similar to measuring DPOAE in the guinea pigs under physiological condition.

  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2004年04期
  • 【分类号】R764
  • 【被引频次】2
  • 【下载频次】88
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