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卵磷脂微乳的流变学特性

Rheological Characteristic of Microemulsion Including Phosphatidycholine

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【作者】 张莉张志荣吴文超陈槐卿向东

【Author】 Zhang Li 1 Zhang Zhirong 1,△ Wu Wenchao 2 Chen Huaiqing 2 Xiang Dong 11(West China School of Pharmacy,Sichuan University,Chengdu 610041,China)2(Institute of Biomedical Engineering,Sichuan University,Chengdu 610041,China)

【机构】 四川大学华西药学院四川大学生物医学工程研究室四川大学华西药学院 成都610041成都610041成都610041

【摘要】 采用 L ow Shear- 30流变测定仪研究 W/O型微乳的不同比例处方 ,在由高到低不同切变率的作用下 ,观察其表观黏度和黏弹性的特性 ,发现随着水分含量增高 ,不同切变率下的表观黏度在不同温度下表现不同 ,而以低切变率下的曲线上升得更陡直。黏性分量 (η′)和弹性分量 (η″)在水分增高时 ,亦作指数曲线样增高。讨论了黏性分量和弹性分量的物理意义 ,以及它们作为微乳的客观定性指标

【Abstract】 This study aimed to evaluate the rheological characteristic of W/O microemulsion. Using the Low Shear-30 Sinus Rheometer,we assessed the effects of water percentage in microemulsion on the apparent viscosity of microemulsion at different shear rates and temperature,and on the viscoelasticity of microemulsion.The results demonstrated that with the increase of water,the apparent viscosities at four different shear rates increased exponentially.The fitted curve between water percentage and the apparent viscosity(η) at low shear rate was steeper than the others. We found that viscous component(η′ ) and elastic component (η″ )also increased exponentially when water percentage was increasing. This communication addressed the relationship between water percentage and η, and discussed the physical meaning of the elastic component.The results suggest that both the viscous component and the elastic component present qualitatively physical nature,but the viscous component is more accurate than the other.

【基金】 国家杰出青年基金资助项目 ( 3 992 5 0 2 5 )
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2004年03期
  • 【分类号】TQ460
  • 【被引频次】3
  • 【下载频次】230
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