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肺毛细血流的氧输运
Oxygen Transport in Pulmonary Capillaries
【摘要】 根据片流模型的思想 ,将氧气通过呼吸膜向肺毛细血管扩散传递过程看成是氧气通过呼吸膜扩散进入血浆 ,再由血浆经红细胞膜进入红细胞的过程。在此基础之上 ,根据红细胞内氧浓度与血红蛋白浓度和血氧饱和度的关系 ,以及血氧饱和度与氧分压的关系 ,推导建立了肺毛细血流的氧输运方程。运用 L ax- Wendroff差分格式求解该方程 ,探讨了静息状态、剧烈运动、呼吸膜增厚以及贫血等生理情况下毛细血流中的氧输运 ,且探讨了周期性脉动血流对毛细血流氧输运的影响。所得结果为医务工作者提供了有意义的参考数据
【Abstract】 Based on the principles of the sheet flow model, oxygen transport in pulmonary capillaries was considered as a process in which oxygen first enters plasma through the respiratory membranes, and then combines with the Hbc. A novel mathematical model about oxygen transport in pulmonary capillaries was established according to the relationship of the oxygen concentration inside the red blood cells with the concentration of haemoglobin and the blood saturation, and according to the basic formula for the correlation between blood saturation and oxygen partial pressure. Furthermore, we adopted the Lax Wendroff Finite Difference Method and obtained certain valuable results under different physiological states. It was well concluded that the established model could be used to provide useful data for medical researchers as well as doctors.
【Key words】 Oxygen diffusion transfer Pulmonary capillaries Respiratory membrane;
- 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2004年02期
- 【分类号】R318.01
- 【被引频次】5
- 【下载频次】96