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工艺参数对超临界CO2抗溶剂法制备乙基纤维素微囊的影响

Effects of Processing Parameters on Ethyl Cellulose Microencapsulation Using Supercritical CO2 Antisolvent Precipitation

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【作者】 张岩陈岚李保国华泽钊伍贻文刘哲鹏陆伟跃

【Author】 ZHANG Yan1,CHEN Lan1,LI Bao-guo1,HUA Zhe-zhao1,WU Yi-wen1,LIU Zhe-peng2,LU Wei-yue2(1.Food and Low-temperature Research Institute, University of Shanghai for Science and Technology,Shanghai 200093, China;2.Fudan University, Shanghai 200032, China)

【机构】 上海理工大学食品与低温研究所复旦大学复旦大学 上海200093上海200093上海200032上海200032

【摘要】 利用超临界CO2抗溶剂法从乙基纤维素和丙酮溶液中制得了乙基纤维素微囊,考察了温度、压力、溶液浓度和搅拌速度等工艺参数对物性的影响,试验结果表明:超临界CO2抗溶剂法可用于食品材料的微囊制粒,所得乙基纤维素微囊的粒径在2.66~9.49μm之间;随着温度和溶液浓度的增加,颗粒粒径及其粒径分布增加;随着压力和搅拌速度的增加,颗粒粒径及其粒径分布减小。

【Abstract】 Microencapsulation of ethyl cellulose was obtained from a solution of ethyl cellulose in acetone using the supercriticalCO2 antisolvent precipitation (SAS). The effects of temperature, pressure, liquid solution concentration, and stirring rate on thephysical characteristics of ethyl cellulose microencapsulations were studied. The mean diameters of the microencapsulationranging between 2.66 and 9.49μm could be obtained. The particle size increase and the particle size distributions enlargementwith the increasing of temperature and solution concentration were found. The particle size decrease and the particle sizedistributions reduction with increasing of pressure and stirring rate were also observed.

【基金】 国家自然科学基金项目(No.59836240)
  • 【分类号】TS20
  • 【被引频次】2
  • 【下载频次】154
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