【摘要】 目的 研究阿托伐他汀对冠心病患者C反应蛋白及血脂的影响。方法 54例冠心病患者检予阿托伐他汀10mg口服,1次·d-1,疗程4周,观察服药前后血清C反应蛋白及血脂浓度的变化。结果 应用阿托伐他汀治疗后,血清C反应蛋白、胆固醇、甘油二脂、低密度脂蛋白水平显著降低,高密度脂蛋白水平明显升高。结论 阿托伐他汀对冠心病患者具有调脂、抗炎作用。更多还原

【Abstract】 Objective To investigate the effect of atorvastatin on C-reactive protein and blood lipids in coronary heart disease (CHD) patients. Methods Storvastatin 10 mg was orally employed for 4 weeks in 54 CHD patients to investigate the changes of plasma concentration of C-reactive protein and blood lipids before and after medication. Results Plasma C-reactive protein, cholesterol, triglycerin and low - density lipid protein were significantly decreased after atorvastatin administration; whereas high-density lipid protein imperatively increased. Conclusions Atorvastatin demonstrated blood lipid regulation and anti - inflammation effects in patients with coronary heart disease.更多还原