【摘要】 通过查阅近几年的文献,综述了来曲唑的药效研究、临床研究的现状。研究结果显示,来曲唑作为新一代非肾上腺皮质类固醇药物,是一种口服的高选择性强效芳香化酶抑制剂。2.5mg来曲唑对晚期乳腺癌的疗效优于标准治疗剂量的氨鲁米特(AG)和甲地孕酮,且毒副作用轻微。更多还原

【Abstract】 Through the pharmacodynamics and clinical studies of Letrozole, a highly selective potent nonsteroidal inhibitor ofaromatase was reviewed. Response rate of Letrozole in 2.5mg was superior to standard dose of Aminogluthimide and Megestrol acetate.Side effects of Letrozole were slight at the same time.更多还原